Eurycoma longifolia JACK and orientation activities in sexually experienced male rats
Address
School
of Pharmaceutical Sciences, University of Science Malaysia, Penang.
Source
Biol
Pharm Bull, 21(2):153-5 1998 Feb
Abstract
The effects of Eurycoma longifolia JACK were studied
on the orientation activities of sexually experienced male rats
towards receptive females (mounting, licking, anogenital sniffing),
environment (exploration, raring, climbing), themselves (genital
grooming, non-genital grooming) and mobility (unrestricted, restricted)
after dosing them with 200, 400 and 800 mg/kg body weight twice
daily for 10 d prior to the test. The results showed that E. longifolia
JACK modified the orientation activities of the treated male rats
in that they significantly displayed more frequent and vigorous
mounting, licking and anogenital sniffing towards the receptive
females, and it further intensified self orientation as indicated
by the increased grooming of the genitals compared to the controls
(p<0.05). In addition, rats treated with 800 mg/kg of methanol,
water and butanol extracts of E. longifolia JACK
continued to show confinement to a particular area of the cage
(around the female), thus showing restriction in movement as compared
to the controls (p<0.05). However, the treated males possessed
a lack of interest in the external environment as indicated by
a reduction in exploration, raring and climbing on the cage wall.
Hence, the present study further supports the folk use of E. longifolia
JACK as an aphrodisiac.
Language
Plant Extracts PD ; Sex Behavior, Animal DE
Animal ; Female ; Male ; Plants, Medicinal CH ; Rats ; Support, Non-U.S. Gov't
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