Eurycoma longifolia increase sexual motivation in sexually naive male rats

Author

Ang HH ; Sim MK

Address

School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia.

Source

Exp Anim, 46(4):287-90 1997 Oct

Abstract

The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days. Results showed that E. longifolia Jack produced a dose-dependent increase in mounting frequency of the treated animals with 400 mg/kg of chloroform, methanol, water and butanol fractions resulting in mounting frequencies of 5.3 +/- 1.2, 4.9 +/- 0.7, 4.8 +/- 0.7 and 5.2 +/- 0.1, and 800 mg/kg further increased them to 5.4 +/- 0.8, 5.4 +/- 0.8, 5.2 +/- 0.6 and 5.3 +/- 0.2 respectively but there were no erections, intromissions, ejaculations or seminal emissions during the 20-min observation period which allowed for the measurement of sexual arousal reflected by mounting frequency uninfluenced by other behavioural components. This study provides evidence that E. longifolia Jack is a potent stimulator of sexual arousal in sexually vigorous male rats in the absence of feedback from genital sensation.

Language

Eng

Unique Identifier

98015053

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Major MeSH Headings

Libido ; Plant Extracts PD ; Plants, Medicinal ; Rats, Sprague-Dawley PX ; Sex Behavior, Animal DE

Minor MeSH Headings

Animal ; Aphrodisiacs AD ; Dose-Response Relationship, Drug ; Male ; Plant Extracts AD ; Rats ; Support, Non-U.S. Gov't

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Publication Type

JOURNAL ARTICLE

ISSN

1341-1357

Country of Publication

JAPAN

Entry Month

9802

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